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This reprint, edited by Prof. Gaetano Santulli, MD, PhD, collects the most up-to-date peer-reviewed scientific papers dealing with cardiovascular medicine, from basic science to pre-clinical and clinical investigations, highlighting the fundamental importance of translational medicine in the challenging quest for new therapies to cure cardiovascular disease. Indeed, cardiovascular disease is the leading cause of death worldwide, and the search for novel mechanisms and therapeutics is desperately needed. Therefore, both basic and translational studies in the cardiovascular field represent a paramount strategy to identify novel therapeutic targets and improve the quality of life of patients with cardiovascular disorders.

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There is growing evidence that among persons with disordered eating behavior, the identification of an "addictive-like eating" phenotype for some persons could be relevant and improve our ability to design better tailored interventions. This "addictive-like eating behavior" phenotype encompasses different terms or concepts, including "food addiction", "eating addiction", "compulsive eating behavior", and "food craving", but also applies to some persons with binge eating disorder, bulimia nervosa, anorexia nervosa, or binge eating symptoms. Although these terms may theoretically refer to different underlying causes or conceptualizations of addictive-like eating, all agree on the complex and multifaceted public health problem it represents and on the similarities it shares with other addictive disorders in terms of etiology, epidemiology, and treatment. Addictive-like eating behavior can deleteriously impact the patient's outcome and may lead to poorer weight loss evolution, increased prevalence of co-occurring medical and/or psychiatric disorders, and/or lower quality of life. One of the key challenges for the present and future research is to better identify this subpopulation of patients exhibiting this addictive-like eating phenotype, and to identify the psychological/psychiatric factors and biological mechanisms underlying this increased vulnerability to addictive-like eating. Such preliminary knowledge is crucial for enabling the development of interventions targeting these vulnerability risk factors and, ultimately, improving patient outcomes.

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Esta investigación analiza los niveles de ansiedad-rasgo y ansiedad-estado, modificando una ansiedad-estado como un estado emocional inmediato, evolucionando en el tiempo. Mientras que la ansiedad rasgo se refiere a diferencias individuales relativamente estables en la ansiedad. Tuvo como objetivo determinar niveles de ansiedad estado - rasgo en tiempos de pandemia Covid-19 en trabajadores de Red de Salud Angaraes - Huancavelica, 2021. Metodología: investigación básica, nivel descriptivo, método analítico sintético, diseño no experimental, transaccional, descriptivo, técnica utilizada, encuesta, se utilizó Inventario Ansiedad Rasgo Estado (IDARE), se tuvo muestra de 110 trabajadores. Resultados: Concerniente a niveles de ansiedad estado, se evidencia nivel bajo 7,27%, nivel medio 41,82% y 50,91% nivel alto. Respecto a ansiedad rasgo, 6.36%, nivel bajo, 40,91 % nivel medio y el 52,73% nivel alto. Respecto al género para ansiedad estado, para femeninos 2.73% nivel bajo, 20.00% nivel medio y 30.91% nivel alto; para masculinos, 4,55% nivel bajo, 21,82% nivel medio y 20,00% nivel alto. De acuerdo con el género, ansiedad rasgo, femeninos presentan 1,82% nivel bajo, 20.00% nivel medio y 31,82% nivel alto. Género masculino presentan 4,55% nivel bajo, nivel medio 20,91% y 20,91% nivel alto. Respecto a edad, trabajadores de 21 a 30 años presentan ansiedad estado en nivel bajo (2,7%), 22,7% nivel medio, y 9,1% nivel alto; de 31 a 40 años 2,7% nivel bajo, nivel medio 13,6%, y 34,5% nivel alto. Conclusión: Los trabajadores de la Red de Salud Angaraes, presentan nivel alto de ansiedad estado 50,91%, respecto a ansiedad rasgo, presentan un nivel alto 52,73%.

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There is growing evidence that among persons with disordered eating behavior, the identification of an "addictive-like eating" phenotype for some persons could be relevant and improve our ability to design better tailored interventions. This "addictive-like eating behavior" phenotype encompasses different terms or concepts, including "food addiction", "eating addiction", "compulsive eating behavior", and "food craving", but also applies to some persons with binge eating disorder, bulimia nervosa, anorexia nervosa, or binge eating symptoms. Although these terms may theoretically refer to different underlying causes or conceptualizations of addictive-like eating, all agree on the complex and multifaceted public health problem it represents and on the similarities it shares with other addictive disorders in terms of etiology, epidemiology, and treatment. Addictive-like eating behavior can deleteriously impact the patient's outcome and may lead to poorer weight loss evolution, increased prevalence of co-occurring medical and/or psychiatric disorders, and/or lower quality of life. One of the key challenges for the present and future research is to better identify this subpopulation of patients exhibiting this addictive-like eating phenotype, and to identify the psychological/psychiatric factors and biological mechanisms underlying this increased vulnerability to addictive-like eating. Such preliminary knowledge is crucial for enabling the development of interventions targeting these vulnerability risk factors and, ultimately, improving patient outcomes.

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Emergency Medical Technicians (EMTs) must be prepared for an array of possible emergencies while on duty. These skills must be ingrained through practice to withstand the stress of an emergency scene: ready at a moment’s notice, should the patient condition necessitate. Within this book you will find many of the skills an EMT will be expected to perform. Each student is required to complete each skill a minimum number of times. This effort will assist the instructional team in tracking your progress, as well as provide you with the documentation necessary to prove proficiency for national and state certification. The skills in this text are important to master but remember, a truly proficient EMT is refreshing old skills and acquiring new ones throughout their career.

Medicine